The Ras switch in structural and historical perspective
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Atorvastatin inhibits insulin synthesis by inhibiting t | Open-i
Pharmaceuticals | Free Full-Text | A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders
Frontiers | The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements - ScienceDirect
Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators - ScienceDirect
The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants - Pálfy - 2022 - Chemistry – A European Journal - Wiley Online Library
Integrated RAS signaling defined by parallel NMR detection of effectors and regulators | Nature Chemical Biology
Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation | Journal of Medicinal Chemistry
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation | Journal of Medicinal Chemistry
A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation | PLOS ONE
Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain | Scientific Reports
Simulating Ras: 30 years of progress - NCI
The current state of the art and future trends in RAS-targeted cancer therapies | Nature Reviews Clinical Oncology
JPM | Free Full-Text | Targeting KRAS in Pancreatic Cancer
Mechanism-Based Redesign of GAP to Activate Oncogenic Ras | Journal of the American Chemical Society
NIH 3D - Ras:SOS:Ras in complex with a small molecule activator
The complex RAS circle shows the interconnections and feedback of the... | Download Scientific Diagram
Competitive, connective and allosteric Nanobodies that modulate the SOS1•RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design | bioRxiv
Ras Laffan Petrochemical Project | Chevron Phillips Chemical
